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Clinical Epidemiology Research Center (CERC)

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Studies and Initiatives

CSP #2032 VA Causal Inference Enterprise (VA CAUSAL)

Executive Committee:

Mihaela Aslan (West Haven CSP-CERC)

Ryan Ferguson (Boston CSPCC)

Miguel Hernán (Harvard)

Grant Huang (ORD)

Rachel Ramoni (ORD)

Coordinating Center - West Haven CSP Clinical Epidemiology Research Center (CSP-CERC):

Mihaela Aslan, Director

Renato Polimanti, Associate Director for Scientific and Technical Operations

Patricia Crutchfield, Program Manager

Implementation and Research Operations Core:

Mihaela Aslan (West Haven CSP-CERC), Co-Director

Ryan Ferguson (Boston CSPCC), Co-Director

Sonia Anand (Boston CSPCC)

Patricia Crutchfield (West Haven CSP-CERC), Program Manager

Methods Core:

Kelly Cho (Boston CSPEC)

Barbra Dickerman (Harvard), Co-Director

Hanna Gerlovin (Boston CSPEC), Deputy Director

Miguel Hernán (Harvard), Co-Director

Constance Hoag (Boston CSPEC), Program Manager

CSP #2038 COVID-19 Pharmacotherapy Effectiveness in the VA Healthcare System (COPE-VA)

Kristina Bajema, MD, & George Ioannou, MD (VA Portland and VA Puget Sound Health Care System), Co-Chairs

Mihaela Aslan, PhD (West Haven CSP-CERC), Director

Rene LaFleur (West Haven CSP-CERC), Project Manager

Lei Yan, PhD (West Haven CSP-CERC), Lead Statistician

Steering Committee:

Mihaela Aslan (West Haven CSP-CERC)

Kristina Bajema (Portland Healthcare System), Co-Chair

Marie Bradley (FDA)

Timothy Buchman (BARDA)

David Bui (Portland Healthcare System)

Wendy Carter (FDA)

John Concato (FDA)

Fran Cunningham (PBM)

Richard Forshee (FDA)

Grant Huang (ORD)

Yuan Huang (West Haven CSP-CERC)

Gabriel Innes (FDA)

George Ioannou (VA Puget Sound Healthcare System) Co-Chair

Amy Kilbourne (ORD)

Rene LaFleur (West Haven CSP-CERC)

William Lance (West Haven CSP-CERC)

Alysia Maffucci (West Haven CSP-CERC)

Natasha Pratt (FDA)

Motiur Rahman (FDA)

Kimberly Sciarretta (BARDA)

Rachel Thompson (FDA)

Stephanie Troy (FDA)

Lei Yan (West Haven CSP-CERC)

Yinong Young-Xu (PBM)

Coordinating Center - West Haven CSP Clinical Epidemiology Research Center (CSP-CERC):

Mihaela Aslan (West Haven CSP-CERC), Director

Rene LaFleur (West Haven CSP-CERC), Project Manager

William Lance (West Haven CSP-CERC), ADO

Alysia Maffucci (West Haven CSP-CERC), ADQA

Lei Yan (West Haven CSP-CERC), Lead Statistician

Data Analytics and Methodology Subcommittee:

Mihaela Aslan (West Haven CSP-CERC), Director

Kristina Bajema (VA Portland Healthcare System), Co-Chair

David Bui (VA Portland Healthcare System)

Kei-Hoi Cheung (West Haven CSP-CERC)

Yuan Huang (West Haven CSP-CERC)

Denise Hynes (VA Portland Healthcare System)

George Ioannou (VA Puget Sound Healthcare System) Co-Chair

Yuli Li (West Haven CSP-CERC)

Hung-Mo Lin (West Haven CSP-CERC)

Pradeep Mutalik (West Haven CSP-CERC)

Rajeevan Nallakkandi (West Haven CSP-CERC)

Vyshnika Sriskantharajah (VA Puget Sound Healthcare System)

Robert Vergun (VA Portland Healthcare System)

Edwin Wong (VA Puget Sound Healthcare System)

Kristin Wyatt (VA Puget Sound Healthcare System)

Lei Yan (West Haven CSP-CERC)

Collaborators:

Amy Bohnert (VA Ann Arbor Healthcare System)

Sheldon Brown (VA Bronx Healthcare System)

Lauren Epstein (VA Atlanta Healthcare System)

Adit Ginde (UCHealth Emergency Care, Aurora CO)

Matthew Maciejewski (VA Durham Healthcare System)

Vincent Marconi (VA Atlanta Healthcare System)

Richard Murphy (VA White River Junction Healthcare System)

CSP #566 - Neuropsychological and Mental Health Outcomes of Operation Iraqi Freedom (OIF): A Longitudinal Cohort Study

Jennifer J Vasterling, PhD (Boston Healthcare System), Study Chair

Mihaela Aslan, PhD (West Haven CSP-CERC), Director

Patricia Crutchfield (West Haven CSP-CERC), Program Manager

CSP #2012 - Leveraging Electronic Health Information to Advance Precision Medicine (LEAP) Program Initiative

Jennifer Lee, MD, PhD & Mei-Chiung Shih, PhD (VA Palo Alto Health Care System), Co-Chairs

Natalie Fullenkamp, MA (VA Palo Alto Health Care System), LEAP National Coordinator

Mihaela Aslan, PhD (West Haven CSP-CERC), Director

Julie Lynch, PhD & Kyung Lee, PhD (VA Salt Lake City), Co-Investigators

Patricia Crutchfield (VA Connecticut Healthcare System), Program Manager

CSP#2006: Genomics of Gulf War Illness in Veterans  

Drew Helmer, MD, & Elizabeth Hauser, PhD (VA Houston and VA Durham Healthcare System), Co-Chairs

Mihaela Aslan, PhD (West Haven CSP-CERC), Director

Rene LaFleur (VA Connecticut Healthcare System), Project Manager

CSP #572 - Genetics of Functional Disability in Schizophrenia and Bipolar Illness

Philip D. Harvey, PhD (VA Miami Healthcare System), Study Chair

Mihaela Aslan, PhD (West Haven CSP-CERC), Director

Alysia Maffucci (West Haven CSP-CERC), Project Manager

CSP #575B - Genomics of Posttraumatic Stress Disorder in Veterans

Murray B Stein, MD, MPH (VA San Diego Healthcare System), Study Chair

Joel Gelernter, MD (VA Connecticut Healthcare System), Study Chair

Patricia Crutchfield (West Haven CSP-CERC), Project Manager

POLYPHARM01 - Treatment patterns, safety & comparative effectiveness of Dolutegravir-based regimens in the older HIV positive population

Mihaela Aslan, PhD (West Haven CSP-CERC), Director

Vales Jeanpaul (West Haven CSP-CERC), Project Manager

Lei Yan (West Haven CSP-CERC), Lead Statistician

Informatics/IT Data Epidemiology Analytics for a Learning Healthcare System (IDEAL)

Primary purpose
The primary purpose of IDEAL is to develop a clinical research focused set of approaches, resources, and infrastructures for achieving a VHA Learning Healthcare System goals.

​​​​​​​The objectives include establishing a robust clinical research enterprise using data driven capabilities and strategies; creating opportunities for partnerships to advance research and care; and using VA data to improve and enhance researcher's activities and products, not only for CSP, but for the broader ORD and VA research community.

Infrastructure Initiatives

Enabling Technologies for Rapid Learning Health Systems (ENTHRALL)
Nhan Do, MD, Director, MAVERIC
Nathanael Fillmore, PhD, Associate Director for Data Sciences, Boston CSP Informatics Center
Danne Elbers, PhD, Associate Director for Data Engineering, Boston CSP Informatics Group

CSP Epidemiology Analytics Resource (CSPEAR)
Eva Thomas, MPH, Project Manager & Data Analyst, Seattle ERIC

Integrated Veteran Epidemiologic Study Data Resource (INVESTD-R)
Jen Sporleder, BS, Associate Center Director, Seattle ERIC

Center for Data and Computational Science (C-DACS)
Samantha Tweedie, MPH, Scientific Program Manager, Boston GenISIS

Approaches to Real World Evidence Initiatives

Leveraging Electronic Health Information to Advance Precision Medicine (LEAP)
Natalie Fullenkamp, PhD, National Coordinator, Palo Alto

Point-Of-Care Research (POC-R)
Ryan Ferguson, ScD, Director, Boston CSPCC

VA CAUSAL Inference Enterprise (VA CAUSAL)
Patricia Crutchfield, Project Manager CSP CERC

Translational and Partnered Data Use Activities

Big Data-Scientist Training Enhancement Program (BD-STEP)
Frank Meng, PhD, Program Director
Kelly Gaynor, MPH, Program Manager
Colleen Shannon, MPH, Deputy Director

IDEAL Partners

CSP IT Strategic Planning Committee
Kousick Biswas, Director Perry Point CSPCC

​​​​​​​IDEAL Coordinator:
Rene LaFleur, MS, ​​​​​​​Research Coordinator, West Haven CSP CERC

EPI Quality Management System
Alysia Maffucci, JD, Associate Center Director for Quality Assurance (ACDQA)
Kristy Goodrich, MS, Assistant for Quality Assurance

Own The Moment (OTM)

When we have the privilege of interacting with a Veteran through our work, we can do much to recognize and value them. The “Own the Moment” initiative within CSP is aimed at helping all CSP staff (and potentially a broader research community) learn ways to better show them that they are the “why” behind what we do.

VA CSP Knowledge, Information Transfer, and Education (KITE) Speaker Series

The KITE speakers series offers conversations with past and present CSP and other VA research leaders who will share their perspectives on a wide range of topics and provide real-life examples of their leadership in action.  By capturing, sharing, and documenting this institutional memory, the Program’s ability to serve as a model for the VA research enterprise will be enhanced, while integrating its activities with VA’s broad network.  

Specialty Areas, Affiliations, and Partnerships

Biomedical Informatics & Data Science

Epidemiology

Biostatistics

General Medicine

Psychiatry

Human Genetics

Veteran Aging Cohort Study (VACS)

VA COVID-19 Observational Research Collaboratory (CORC)

Biomedical Advanced Research and Development Authority (BARDA)

U.S. Food and Drug Administration (FDA) Center for Drug Evaluation and Research (CDER)

VA Connecticut Research and Education Foundation (VACREF)

ViiV Healthcare Limited Pharmaceutical company